Evolutionary triangulation: informing genetic association studies with evolutionary evidence

Optimal Triangulation by Means of Evolutionary Algorithms

Usually, three-dimensional objects cannot be scanned in one pass, but must be measured in a series of linear scans along parallel scan lines. Simple triangulation methods make use of the line structure of this kind of scans by keeping the scan lines fixed and calculating zig-zag paths between each pair of adjacent scan lines. The success of those strategies highly depends on the appropriate dir...

An Evolutionary Algorithm for Bayesian Network Triangulation

The problem of triangulation (decomposition) of Bayesian networks is considered. Triangularity of a Bayesian network is required in a general evidence propagation scheme on this network. Finding an optimal triangulation is NP-hard. A local search heuristic based on the idea of evolutionary algorithms is presented. The results obtained using existing and proposed approaches are compared on a bas...

Toward Evolutionary Innovation Theory

Abstract: Innovations, commercialized by new or old established firms, located at the core of industrial renewal process. The innovation concept has suffered transformations, along with the evolution of the models that try to explain and understand the innovation process. The innovative process corresponds to all activities that generate technological changes and the dynamic interaction between...

An Evolutionary Framework for Association Testing in Resequencing Studies

Sequencing technologies are becoming cheap enough to apply to large numbers of study participants and promise to provide new insights into human phenotypes by bringing to light rare and previously unknown genetic variants. We develop a new framework for the analysis of sequence data that incorporates all of the major features of previously proposed approaches, including those focused on allele ...

Studies in Evolutionary Algorithms